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Weigh water and food together, subtracting any bone weight, since salt will not diffuse into bones.
Multiply the combined weight of the water and meat by the desired finished salinity you want your protein to contain at the end of the brining process (usually ½ to 1% by weight).
Dissolve the appropriate amount of salt into the water and place food in the brine. Use a salinity meter to monitor the process and when the brine's salinity drops to half, we have equilibrium.
* minutes
** multiply by 16 for ounces, and again by 28.3495 for grams
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